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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0453b97582ad908c1a155e8c4d5652fe4d18b2f64c031be4270b7c9c8661cb67' 
  AND token = '76P9kWhcPMUG+UpgYb9gQork4faKnWipLrxGZxH7jTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}