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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df7636c8c37945deef90b5f51581ceece6ef6d75aa5f31b3e20cd677da0c02aa' 
  AND token = 'dmW9Wyl6OrsPybJYDgVkuP6KV6iFQkaouTy0xCfEvgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}