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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0ea8268e71a3dfb7f94fdaf7b4dda142bc15145530ec34c927113d838f00ab0' 
  AND token = 'RETO67NLVD+ZcnVe54+p2u6s8WHfwaaQOmEtAy7DiuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}