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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ceca374b449b9e214ae9da6b0f59191ff4d5acafc29fb2cc9514c100418568b2' 
  AND token = 'jryTmBjxehwVDeCRPeld7otWclSgMHO+F+ntRb20FJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}