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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8925c9f17b53e409e3c3866e0c2ed63ad3c9e3005ba07aa2fc9b1ae09136542' 
  AND token = 'HTH383qxiVASbMGMsTAITOpc0LtwwBDm7yqo/PXOfHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}