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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d93b1c4be82b2965ff57b094a4259fbcdc3ed14bb98955bfba42417426d8565' 
  AND token = '1qc4ZrYwRKoZ+S6Sm50UdlPXH2NyyIhYxz+rWzSbzTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}