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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f09d06605e3811f1b29cd014b69a945d8d1c84ea87ed555c61f185af71c3541' 
  AND token = 'yrVYBZHH80V7mEfrMJBIzDLRhmBTcgRasdGcT6Z7i9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}