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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd84149f201072572037110d96e3491ed91d902e42cb593ceb92caa1d664308d0' 
  AND token = '+V+TVc2h0IJfsMl6EUS1nGIADTX+4YIEFrMrt0LhiTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}