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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ca5450f6616ad8458650ac52ddf8ed490eb9211624d235da90a15eda5cf31e3' 
  AND token = '/X7edqCUkhTlyqlqX8mP7cDshyC6tJMjwgME6vd7IYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}