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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e494f3825a2e5879847e1516596dca61c9e03149af4dfc46acefdc31e05ba650' 
  AND token = 'v2HzLj4e+sFqvmi31jFpNkdsCobEQxOr7OsOqUXTb0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}