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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f256fe236f76a257787a13c6edc7e2723bcfa15fa274175c4573059655be1ea' 
  AND token = 'jGEBOJcuxOpLKqLezasizlt7DtRJV5vh3TXPPlyd324=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}