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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '322fc028d1bc3eb9cafceacd1f281ac7d54ffaf0fa548109f17d4274a39dfcda' 
  AND token = 'tlddJbOxA1Mfblowk6NmS8s3eJdOiC+YqgCKB/CQ7bo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}