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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d0e8676350aaa39b24fc44107d91c1ec83959645394e1ca957b9c85f89ab31e' 
  AND token = '+PU1Iz1Ds5Yrp0PFDuLjWuyQb5r6cnmwhvRSIiF3nwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}