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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b484095639e82147956d64ae463907c5e5915728044821aa62eabf6de4a99518' 
  AND token = 'EWOMG8a+e9/x2Hh4Drwgrk+0IE7MR2BvZ3qMV3EoMP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}