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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d2f399b5e9e67110aa10631d490ed43e785eefbd0270443015ceeb8d6dfdca1' 
  AND token = '2HEbRIMQJ9DZOK+6bY5hn8lo49q+YYGGk4nwtotMN64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}