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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49a38bfcbf2adb066bde050b97a1685a062f25f80d7238418d8d920efba0277d' 
  AND token = 'cR+dUkkwMJG32RDaYRiA4q+24ebwN2EWRlfhWohYeW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}