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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7961f6700e530e58bd43ca31e849a8f114fe8b28dd12372c1aed5bc150367f95' 
  AND token = '4/RCv8Gt2DBqq7L/FOpeTE4j2OwwIVNowNfXd25jm3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}