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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46c609ddbb909bd3a8e0536269964a7d6295df2125f9f1c5d34c24fcd332a84f' 
  AND token = 'hQMi1E5XDsgsLl7p0pRe+gTWVCP9hpcoCQ2977oAAqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}