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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16048446d577d807644dc20234b289d127fbf1b906d92b4a09ac855415efe0b5' 
  AND token = 'sHR8Z/VpjqwJn04dIdNU/CFbUJdAxW34mlF0fGOWwQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}