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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6e1705588a9308fd4e19a7c2bb55a109cfb910c7cc097eb3b1a0cfe716afce7' 
  AND token = 'C6k+yhjbKwkpJ47NFfiym0dqIzb88qOlBAV7Ny0QEBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}