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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4dbf85c278a65384f5e2e20460de4a3a3927cd4a3fed9f4007775818311617e' 
  AND token = 'IMxs1gBlHub+hvUhYVvE+6gHP4yO77YhTM17k3R2DTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}