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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5581a8b761bc5e92739862d1554b2d94a917bfaa81c6573c2eb89125436a7bbb' 
  AND token = 'L30TOPsIh5j4FGYD6hDyqFZjabj3sG2b3i+jZ/x2QAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}