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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36362d755cd177e2654053054e08541d54d201b711a7a0b1f24b6213c0ea7d50' 
  AND token = 'IvcFC1PEc/knyl1PeRO1wqRDV++cHRHOPlFGFw5TEGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}