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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a53cb13cfa36659fc2c9c6b13496c3d5cfa939c7d2c199c5600834f1cb88e46' 
  AND token = 'DYjvCsolYPYy1lc5VaIk8J1blUGmzlN5rdICX4fSMlg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}