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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d460b2d24c8361ba4d26b37499056c43144ef9968c3325ff1b80aa4f220b688' 
  AND token = 'cIcKAcA0jc9V7SKn/j9376urUH6CAXZMmvShflBp94A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}