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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '973d5f43e648b7f016110b2e3b589adb7b19b7584b9c74c26e6e3b4621d0efbf' 
  AND token = '3PEmVORNkDDJdv7RNmBmR91KVbhc0KODYsDq3P7YsEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}