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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5854a7051fa6af15945416c6b5bcd2aaecce37c2c236c3604fe057f1e82aa621' 
  AND token = 'qK1oeSG9gtFKw+P3yjMZ4Gg2tSXqfviIy46yNFdE2P4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}