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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da216a6ade92eafa0f6017089f0c76bca79a992d90332106e9f985a8312f6d1b' 
  AND token = 'M5rpvsCSR5hTuLeuEpOIylEn9hs9aTbD87TtzAxAQsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}