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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2beef5f6fb878b24c6c32af8ca102bd3f7a9de4ade042643421265cb51398f12' 
  AND token = 'MP0sMnAO9wbRTAg+3N4djqS8TzjnbMAbwoeBtNS2HeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}