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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f05b7f7c2d9b0d7744e9330bcfb95b8c1ad89b766f72f98c291f184998022f89' 
  AND token = '+yRGuW5xc8HLnckL2axINu7OH2oZdkptTvnBuC8MdIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}