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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01b8a4b9e37177b2881d5826a585ee665fba1a7f1a532b3c8e0d1d6b61c9a8d0' 
  AND token = 'QkVJu+VTKpoNy7HywuZm3p63/keQCOjPbYoG3ryyAiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00065

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}