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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e950d8a237fba17adc88c33da9cd81549a2c3af24b5ed50ee1e328185ae05f6' 
  AND token = '4JpjCU6/Z/EnTR9WAf0MnMq1/S8hqv4RtvXj6d8jkxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}