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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a93cb3f6d94f5e196d5b0a7624a36957c78b3b215caff67be9fa18ada9bebc60' 
  AND token = '+1/s3Cmp8ns3N7R8YmjPrsNNs7tgHyiovb1Sy251B4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}