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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '498252f1f54bd756bac9acc739728dec9ceca0360a2a5b3b7654d00d0e0fcd5e' 
  AND token = 'snZXA12vBa93n/nkVlC5BCyKMGWkE0dz8uMg/JOV9Ug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}