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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '568b00a1ba3bcdac81749f204c903082b9d94c4ff9419f5ea046a979d014b26e' 
  AND token = 'mkkDQ7m86FwyWFAGsUiobWYmmweEMx39k8XpVgENcmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}