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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '335302a742b87b97dd066d1753b020ed012bc580b1e4a0a9a2a8be8f401bfbd9' 
  AND token = 'Mycx787X2Q5U3owxPu9gC/QP2KEsKcPEKDxGJENkgys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}