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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af683ddedc5af25825d6e428769f144193980da1cb85214828ab73b3f5f42da2' 
  AND token = '6H4SWvBwaJhLFvZKtqLa22FtD5aaAcI/Yq/ZWQc38T8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}