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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5317df874592c509ee92de9bfbb6913cfa0b75d288a9e4d7cf15806603759b01' 
  AND token = 'zBieQFOa8a1o6LszXAQN9yfiqIsvWspRkVrMCVBm0xI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}