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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51a8f0d0f4fcdb10eda963fb5a90a6e88f6c42373408a20e996ab14481c65f2f' 
  AND token = 'VOZ2uKedgt+DpXoQXmQkA0fX73YNr1lyvbTgUWsn2qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}