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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b1ed0b2530ead06adfecff7f2e83ee4a896290e5b64cf0e41a7ae2686d43cef' 
  AND token = 'aSWjwfdf7Rl4jsY1bFlQsBizBuvj+fzEiUrNEVlZxrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}