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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb1ee02cd313041c0f347a01341044bf0d4a2c0d5327247bb2caa5cbf61cd3c5' 
  AND token = 'cehMV4+OjwxqjRvhmwkwK/jcM7co3HgvOR1ATYvJWw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}