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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '249624952a371ba8e12e19e77e59334b6b6b71b72b5a604f52285197f7c0de64' 
  AND token = 'AIsDYyysl9hG8ktoeLausiLTvw54O9rafUxrpAzidt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}