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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76f9916980ca7a563448c75919e3ee2050a70cbb1c1fe9727927c9c0b0b1dc5f' 
  AND token = '5/qyDgvApYHMEe3xTUZT+sr++1cOXCY7Gh8uoLCPxzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}