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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f349d9e4dfe1e0e1257370afcd9723c0d939a11a0560d04c8783889e6980d953' 
  AND token = 'xXTJBAIOfS5c0TeWtTalz3eETQCZ9xBeiihewaSp3+w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}