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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4b50dd51f81d0f84b6005abb4ae57eef38ea82bc66730a60b1bb0e9849d9c19' 
  AND token = 'wHlpB6tBbf/DKigAvd9RF4u+wJQBaCL6S2Z7eRqUs0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}