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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66239b5d1d96cc862ec54a49efa7210c7e72795bb74b7ada3e22f1db6fe6647f' 
  AND token = 'TFm0ony0/blL8AC+XDdxpalLYXkK/uyUCaeweLin5zU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}