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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3380e57f3e549ecb867c86f305ffa676d8641c098ef77658b0dc37c1ea7a68b3' 
  AND token = 'zO0F6sg3FLycTVo1KdI/1DAnMtS3Udn9gY5Tf6+Ccoc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}