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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3affa6eae1f4cc73fc98732cce00b135809684ce02116add997b1ff2f13250b6' 
  AND token = 'C6RA/qExwvKuweKiNmQt18BJPTK+Q/AV2W9f0oVo7tQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}