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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fc44eee6305329477e1ada7d6960eaf2b730655b0e6a5f7f61dddf821587a81' 
  AND token = 'ZiUH3ECyB060Hz+ZDKhYXC21s+DJMQIKBnWybwFbF20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}