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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '187cb762b5d89fa9c49acd1d44fd80fa6171e8553074c70cfc3e48f2b316cbe1' 
  AND token = 'RsC97j9mM9NDlXQ8I/2U6BhXQpAa2SPiB8naVEzKltQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}